Advanced practice registered nurse (APRN) vs. nurse practitioner (NP)

After gaining experience in the nursing field, you may be ready to assume more responsibility. Becoming an advanced practice registered nurse (APRN) allows you to do just that. APRNs are extensively trained to diagnose illnesses, deliver services, and care for patients, according to the National Council of State Boards of Nursing (NCSBN). Ultimately, advanced education can prepare you for greater responsibility in the workplace, although the authority you hold depends on the laws of the state where you are licensed.

What’s the difference between an APRN and a nurse practitioner (NP)? NPs are one of four types of APRNs. The other types are certified nurse midwives (CNMs), clinical nurse specialists (CNSs), and certified registered nurse anesthetists (CRNAs). Regardless of which APRN path you choose, these advanced certifications allow you to specialize in an area you feel passionately about and have a deep effect on patients’ lives.

The program cards/tables featured on this page were last updated in October 2026. For the most current program information, please refer to the official website of the respective school.

Sponsored online nursing programs

Simmons University

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Master of Science in Nursing (MSN)

Earn an MSN online from Simmons University. The programs combine live classes, engaging coursework, and hands-on clinical experiences to help you advance your career as an NP. Choose from two program options — FNP or PMHNP — and prepare to raise the standard of patient care. Explore Nursing@Simmons programs for RNs who hold a BSN or bachelor’s degree.

  • Choose from two program options — FNP or PMHNP
  • Complete in as few as 24 months
  • Full-time and part-time tracks available

Georgetown University

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Master of Science in Nursing

Nursing@Georgetown enables RNs to earn their MS in Nursing online from Georgetown University. Through a research-based curriculum and hands-on clinical experiences, the program prepares students to pursue certification in an APRN specialty area and provide specialized care for patients in their communities. BSN required.

  • Earn your MS in Nursing in as few as 23 months
  • Choose from one of four APRN specialty areas: AG-ACNP, FNP, NM/WHNP, or WHNP
  • Gain hands-on clinical experience in evidence-based practice

St. John Fisher University

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Master of Science in Nursing

Earn an M.S. in Nursing online at the Wegmans School of Nursing. Bachelor’s in nursing and RN license-required. The online pathway combines live classes, 600 hours of clinical rotations, and on-campus immersions to prepare you to pursue NP licensure in one of four specialties: PCFNP, PMHNP, AGACNP, or AGPCNP.

  • Part-time and accelerated tracks available
  • Four program options: PCFNP, PMHNP, AGACNP, AGPCNP

What is an APRN?

An APRN or advanced practice registered nurse is a nursing professional with specialized education for a specific patient population or skill set. At minimum, APRNs have a registered nurse (RN) license, graduate-level education in nursing, and national certification in their role, according to the NCSBN’s APRN Consensus Model. Their education and certification prepare them to assess, diagnose, and manage patient problems, order tests, and prescribe medications, but the authority to do so comes from state licensure and law, and regulation differs from one state to another.

As the Nurse Practitioner Certification Board (NPCB) renewal handbook states, certification does not authorize practice beyond the scope permitted by applicable laws, regulations, or licensing authorities. In addition to diagnosing and treating patients, nurse practitioners emphasize disease prevention and patient education, according to the American Association of Nurse Practitioners (AANP), and certified nurse-midwives likewise provide health promotion and disease prevention, according to the American College of Nurse-Midwives (ACNM).

Becoming an APRN gives you the opportunity to work with a specific patient population, making it possible for you to focus on a specific nursing interest. For example, if you know you would like to work with children, you can pursue pediatric clinical nurse specialist certification, such as the ACCNS-P offered by AACN Certification Corporation. For those with the time and resources to pursue additional schooling, becoming an APRN may be one way to advance their career in nursing.

Other titles for APRNs: APN and ARNP

APRN is the umbrella title that the NCSBN APRN Consensus Model uses for nurse practitioners, clinical nurse specialists, certified nurse-midwives, and certified registered nurse anesthetists. Some states use a different formal title, so you may also see APN or ARNP. New Jersey, for example, uses the title advanced practice nurse (APN), as the Governor’s Office announcement of 2026 legislation on APN practice shows, while the Washington State Board of Nursing licenses advanced registered nurse practitioners (ARNPs). Because each state sets its own title and requirements, check with your state board of nursing before you enroll in a program.

Pathway to become an APRN

When deciding on which APRN program to pursue, it’s important to know which career you’d prefer. After becoming an RN, APRN education takes place at the graduate level: NCSBN describes APRNs as educated in a specific role and patient population at a master’s or post-master’s level. Your options include online MSN programs, and formats and schedules vary by school, so confirm them with each program.

Program length and structure vary by pathway. If you’re an RN without a bachelor’s degree in nursing (BSN), an online RN to MSN program is designed to move you to the master’s level. According to the American Association of Colleges of Nursing (AACN), these programs build the missing baccalaureate-level content into the program, and many award both a baccalaureate and a master’s degree; many are delivered largely online or in a blended format.

Upon completion of a graduate program such as an MSN degree, you’ll need to achieve certification in your APRN specialty. A variety of professional organizations offer certifications, including the American Nurses Credentialing Center (ANCC), the American Association of Critical-Care Nurses (AACN), and the American Midwifery Certification Board (AMCB). After becoming certified, you will need to secure a license in the state where you intend to practice. Requirements differ between states, so it’s best to check with yours beforehand.

What is a nurse practitioner?

A nurse practitioner (NP) is a type of APRN. These nursing professionals diagnose and manage acute and chronic diseases, perform physical assessments, create treatment plans, and can prescribe medications in certain states. AANP describes these duties, while the authority to prescribe comes from state law: Washington’s ARNP scope of practice rule, for example, allows licensed ARNPs to prescribe medications when prescriptive authority is granted. NPs specialize in one of several areas: adult-gerontology primary care, adult-gerontology acute care, neonatal nursing, pediatrics, psychiatric mental health, women’s health, or family nursing.

Like other APRN career paths, becoming a nurse practitioner requires completing an accredited graduate-level program (a master’s or doctoral degree, or a post-graduate certificate), passing a national certification exam, and being licensed by your state, as NCSBN and NPCB’s family nurse practitioner candidate handbook describe. It’s important to recognize the time and financial commitment necessary to become an NP, but it may be a worthy investment if you’re ready to take your nursing career to the next level.

Pathway to become a nurse practitioner

Your NP career starts off with obtaining relevant education and training. Before enrolling in any NP program, make sure it’s accredited, since NPCB requires graduation from an accredited program for family nurse practitioner certification. Accredited nurse practitioner programs vary in format and schedule, so confirm the options with each school to find one that best fits your schedule.

As an NP, you can work in a variety of specialty fields. If you’re interested in providing care to women across the lifespan, you may consider a women’s health nurse practitioner (WHNP) program. If you want to work with patients suffering from acute conditions such as respiratory distress syndrome, then you may want to look into completing one of the acute care nurse practitioner (ACNP) programs.

Upon completion of a program, you will have to become certified in your specialty by a board like the ANCC or the American Academy of Nurse Practitioners Certification Board (AANPCB), which operates as the Nurse Practitioner Certification Board (NPCB). Certification requirements often involve an exam, completion of an accredited program, an academic transcript, a minimum number of clinical hours, a nursing license, and a certification fee, as NPCB’s family nurse practitioner candidate handbook shows.

Sponsored online nursing programs

Simmons University

Ad

Master of Science in Nursing (MSN)

Earn an MSN online from Simmons University. The programs combine live classes, engaging coursework, and hands-on clinical experiences to help you advance your career as an NP. Choose from two program options — FNP or PMHNP — and prepare to raise the standard of patient care. Explore Nursing@Simmons programs for RNs who hold a BSN or bachelor’s degree.

  • Choose from two program options — FNP or PMHNP
  • Complete in as few as 24 months
  • Full-time and part-time tracks available

Georgetown University

Ad

Master of Science in Nursing

Nursing@Georgetown enables RNs to earn their MS in Nursing online from Georgetown University. Through a research-based curriculum and hands-on clinical experiences, the program prepares students to pursue certification in an APRN specialty area and provide specialized care for patients in their communities. BSN required.

  • Earn your MS in Nursing in as few as 23 months
  • Choose from one of four APRN specialty areas: AG-ACNP, FNP, NM/WHNP, or WHNP
  • Gain hands-on clinical experience in evidence-based practice

St. John Fisher University

Ad

Master of Science in Nursing

Earn an M.S. in Nursing online at the Wegmans School of Nursing. Bachelor’s in nursing and RN license-required. The online pathway combines live classes, 600 hours of clinical rotations, and on-campus immersions to prepare you to pursue NP licensure in one of four specialties: PCFNP, PMHNP, AGACNP, or AGPCNP.

  • Part-time and accelerated tracks available
  • Four program options: PCFNP, PMHNP, AGACNP, AGPCNP

Advanced practice registered nurse (APRN) vs. nurse practitioner (NP) – what’s the difference?

An NP is one of the four types of APRNs. If you’re interested in pursuing further education and becoming an APRN, it’s helpful to know the differences between each specialty so you can choose a program that fits your interests.

Education and curriculum

NPs and CNSs complete an accredited graduate-level program, either a master’s degree, a Doctor of Nursing Practice (DNP) degree, or a post-graduate certificate, according to NCSBN. Certified nurse-midwives need at least a master’s degree to sit for the AMCB certification exam. All U.S. nurse anesthesia educational programs are at the doctoral level, according to the Council on Accreditation of Nurse Anesthesia Educational Programs (COA). Within these degree programs, students can pursue tracks for particular NP and APRN specialties. Admission requirements vary by university, so check the requirements of each program you are considering.

Accelerated nursing programs make it possible for people with a bachelor’s degree in an unrelated field to transition to nursing. AACN reports that accelerated baccalaureate programs take between 12 and 18 months and accelerated master’s programs generally about two to three years. RNs without a BSN who want a master’s degree can look at the RN to MSN pathway described above. In addition to accelerated programs, there are a number of flexible nursing degree options for students with an array of educational backgrounds. According to AACN, more than 120 dual master’s degrees combine nursing with fields such as business, public health, and health administration, and certificate programs are available to master’s graduates who want to sharpen their skills in a focus area.

The NCSBN Consensus Model calls for APRN programs to include, at a minimum, three separate graduate-level courses: advanced physiology/pathophysiology, advanced health assessment, and advanced pharmacology. Beyond that core, additional content and courses are tailored to the student’s role and patient population.

Skills and certification

NPs share much of the same education as other APRNs, all of whom complete graduate-level preparation. However, each is prepared for a specific role and patient population, and they acquire different skills to do so.

Both NPs and CNSs are APRNs educated in a specific role and patient population. NPs provide direct primary or acute care depending on their population focus, while CNSs work across three overlapping spheres of influence: patients, nurses, and healthcare systems, according to the NCSBN Consensus Model. Certification is separate for each role and population focus, so an NP and a CNS take different exams. For example, AACN offers separate ACNP and CNS board certifications to graduate-educated nurses.

Specialties

Under the category of APRNs, there are four career tracks. In this section, we dive into each one and expand on different nursing specializations so you can better understand the options available.

Advanced practice registered nurses (APRNs)

Nurse practitioner specialties

Choosing an APRN role

Your interests and the patients you want to serve usually point toward one path. A few questions can help you narrow the choice:

Whichever role you choose, confirm the education, certification, and licensure requirements with your state board of nursing before you enroll, because regulation differs from one state to another.

Scope and work setting

In medicine, scope of practice is the range of responsibilities a practitioner is authorized to take on. The scope of practice varies for each APRN specialty. According to NCSBN, APRNs are prepared by education and certification to assess, diagnose, and manage patient problems, order tests, and prescribe medications, although states have not all adopted the same regulatory framework. Some APRNs, including nurse practitioners, can prescribe medications and practice independently in certain states. In Washington, for example, state regulation defines the ARNP as a licensed independent practitioner, and the Washington State Board of Nursing adds prescriptive authority to an ARNP license through a separate application. Across the board, these nurses provide important, comprehensive care for their patients and have a high level of medical knowledge.

Depending on their role, APRNs practice in settings such as hospitals, clinics, private practices and physician offices, ambulatory surgery centers, and community and public health settings, according to AANP, AANA, and ACNM. Some certified nurse-midwives also provide care in patients’ homes and in birth centers.

Salary and career outlook

Advanced nursing roles also have an above-average earning potential compared with registered nurses overall. The list below shows the U.S. Bureau of Labor Statistics (BLS) Occupational Employment and Wage Statistics (OEWS) national estimates for May 2025 for each APRN role that BLS reports as a separate occupation, with registered nurses for comparison. Wages are median annual wages, and employment is estimated national employment.

  • Registered nurses (all): $97,550 median annual wage; 3,379,720 employed
  • Nurse practitioners (NPs): $132,300 median annual wage; 323,040 employed
  • Nurse midwives (CNMs): $134,040 median annual wage; 7,920 employed
  • Nurse anesthetists (CRNAs): $236,590 median annual wage; 51,840 employed

Income for these professions varies by state and city. According to BLS OEWS May 2025 state estimates for nurse practitioners, NPs have the highest estimated employment in Texas (25,970), California (25,120), New York (22,890), Florida (21,790), and Ohio (15,400) — but earn the highest median annual wages in California ($168,520), New Jersey ($159,310), Washington ($156,100), Oregon ($155,680), and Alaska ($155,170). These rankings are our calculations from BLS May 2025 state estimates.

Continuing education requirements

Once you complete your APRN certification, you will have to renew it regularly. Certifying bodies set their own renewal cycles. NPCB, for example, grants family nurse practitioner certification for five years, and family nurse practitioners can renew by examination or by completing practice hours and continuing education, according to NPCB’s renewal handbook. NPCB requires current, active nurse licensure throughout the renewal process.

If you’re interested in furthering your education after completing a master’s program, a DNP program may be for you. The DNP is a practice-focused terminal degree, and AACN reports that DNP programs prepare nurse leaders at the highest level of nursing practice to improve patient outcomes and translate research into practice, with coursework in areas such as evidence-based practice, quality improvement, and systems leadership. Whether you’re hoping to continue clinical practice after graduation or move into a leadership role, check each program’s focus to see whether it includes preparation for an advanced practice role.

Information last updated: October 2026